منابع مشابه
Fatal Nitrofurantoin-Induced Pulmonary Toxicity: A Potentially Preventable Medical Error
The majority of patients affected with nitrofurantoin pulmonary toxicity are elderly women [1]. The proposed mechanism of toxicity is either idiosyncratic oxydant-mediated tissue injury by nitrofurantoin metabolites causing depletion of cellular glutathione (chronic form) or by immunological response induced by nitrofurantoin metabolites acting as heptanes and resulting a hypersensitivity react...
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Granulocyte and granulocyte-macrophage colony stimulating factors (G-CSF and GM-CSF) are haematopoietic growth factors. They stimulate haematopoietic progenitor cells to proliferate and differentiate into granulocytes and macrophages and are used prophylactically during the period of bone-marrow suppression after chemotherapy (1). Anecdotal reports have suggested an increased risk of pneumoniti...
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BACKGROUND Gemcitabine is the only approved cytotoxic agent for the treatment of pancreatic cancer by the Food and Drug Administration. In addition, gemcitabine is also commonly used for the management of breast, ovarian, and non-small cell lung cancer. Myelosuppression is the most common toxicity of gemcitabine therapy. Pulmonary toxicities due to gemcitabine have, however, been reported. Dysp...
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The data we obtained suggested that the changes in the bone mineral content in EDS patients, although less intense than in other hereditary collagen diseases, are also present. Our study also suggests that this reduction in bone mass only affects predominantly trabecular bone. Subsequent studies involving greater numbers of patients and a clarification of the biochemical and genetic mechanisms ...
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Amiodarone-induced pulmonary toxicity is a critical and potentially fatal side effect of amiodarone. Our study was designed to reveal its clinical features, including KL-6, as an interstitial marker. The medical records of eight patients (five men and three women) with amiodarone-induced pulmonary toxicity, who had been referred to our hospital, were examined. The mean age at the initiation of ...
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ژورنال
عنوان ژورنال: American Journal of Hematology
سال: 1999
ISSN: 0361-8609,1096-8652
DOI: 10.1002/(sici)1096-8652(199901)60:1<82::aid-ajh18>3.0.co;2-r